Dear Dr Puff n’Stuff

A friend told me that Father Christmas was originally invented by someone high on magic mushrooms. Is that true, or was he having me on?


No, he’s almost right. The Father Christmas legend developed in Victorian times from a very long tradition in various societies of wizard-like creatures, who would appear at Christmas to reward good children and punish bad ones. The man who first described somebody like our modern Father Christmas was an American written who was familiar with customs in Lapland and Siberia. It is likely that he based his creation on the shamans or witch doctors who practiced their craft in these icy northern regions. The regions are home to reindeers and sledges, and also to an hallucinogenic mushroom called Amanita Muscaria, or Fly Agaric. These mushrooms are white and red, the colour of Santa’s uniform. When shamans eat them, they imagine themselves soaring up through the chimneys of their huts and flying through the skies. They bring back presents of wisdom to their people. All this is very like Santa’s annual journey, and it appears that the shamans have passed on to him the colour of his uniform, his reindeer and sledge, his love of chimneys and his ability to fly.

The Father Christmas legend developed during the nineteenth century, but it was a Coca Cola advertisement at the beginning of the twentieth century, which first showed him in the exact garments with which we are familiar nowadays. And you all know that Coca Cola started off life as a throat medicine containing cocaine. Which all goes to show that drugs are at the root of much more than you realise.

HAPPY CHRISTMAS!!.

Dear Dr Puff n’Stuff

How long do you think it will be before a THC spray is available for personal and private use (not specifically for a medical condition) i.e. for the non-smoker?

THC (tetrahydrocannibol) is the active ingredient of cannabis. Taking cannabis by means of smoking is an important cause of lung disease, both bronchitis and cancer, although of course it is hard to work out how much is due to tobacco and how much to cannabis. In George Harrison’s case, both probably played a large role in his premature and uncomfortable death. It would therefore make a lot of sense if cannabis users could take it by aerosol spray rather than by smoking. The technology is already available, but it is illegal to use cannabis for personal pleasure and so of course the spray cannot be marketed.

Recently the government has permitted the development of cannabis based medicines for use in medical trials. GW Pharmaceuticals are currently conducting a trial of cannabis for multiple sclerosis sufferers, using a device that sprays the drug under the tongue. Apparently this works very well, and patients are making good progress. However, even if the trials are successful it will be two years at lease before cannabis is prescribed routinely by GPs. It takes that long for new medicines to go through all the licensing procedures. There are no plans to authorize prescription of THC for treatment of cannabis dependence.

As for when sprays become available to the general public, this depends on when cannabis is fully legalised (if ever). Your guess is as good as mine, but my prediction is in about ten to fifteen years. Perhaps Father Christmas could help.

Dear Dr Puff n’Stuff

If someone is on a 100mg per day prescription of IV methadone, what would be the ratio used to calculate the same dose of diamorphine, bearing in mind that it could be prescribed as an alternative regime? What are the different cost implications involved and why is it policy to distribute diamorphine in glass ampoules as these take up most of the cost?


Diamorphine lasts about eight hours in the body, while methadone is effective for twenty-four hours. As they are both of similar potency, this means you have to prescribe about three times as much diamorphine per day as methadone. However, I usually find that someone on 100mg IV methadone is likely to require about 400mg diamorphine to be comfortable. This much diamorphine costs about £18 per day, or about £6,500 per year. Two 50mg methadone amps cost £4 per day, or about £1,500 per year. In both cases dispensing charges have to be added, which comes to about £500 a year (for daily dispensing). In other words, the diamorphine would cost the NHS £5000 per year more than the methadone amps. This kind of figure is not calculated to cause delight in our finance departments.


You are right that diamorphine is much cheaper if it is dispensed in the form of powder. 400mg costs £2.60 per day, or £950 a year; not much difference from methadone mixture. We cannot prescribe it in this form for two reasons. Firstly, it is not guaranteed to be sterile. Therefore if you injected it and acquired an infection, you could rightly complain of poor medical practice. Secondly, the Home Office does not allow it. They argue that powder is more easily sold on than ampoules, because it can be readily cut down with other substances. I’m not sure they are right about this, because there is a ready market for diamorphine ampoules. Nonetheless, they are the ones who are in charge.

If a lot of people were prescribed diamorphine, I’m sure the government could negotiate a more reasonable price from the manufacturers. The whole issue of diamorphine prescription is currently being reviewed by the new National Treatment Agency, so watch this space. This could be another request to send up the chimney to Father Christmas (he does look quite like David Blunkett, after all).

Dr P's letters were aimed at our pre-Xmas deadline, but we thought we'd keep his jokes in anyway.

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